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Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial |
journalArticle |
2015 |
Le Tourneau, C.; Delord, J. P.; Goncalves, A.; Gavoille, C.; Dubot, C.; Isambert, N.; Campone, M.; Tredan, O.; Massiani, M. A.; Mauborgne, C.; Armanet, S.; Servant, N.; Bieche, I.; Bernard, V.; Gentien, D.; Jezequel, P.; Attignon, V.; Boyault, S.; Vincent-Salomon, A.; Servois, V.; Sablin, M. P.; Kamal, M.; Paoletti, X.; investigators, Shiva |
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Screening in asymptomatic SDHx mutation carriers: added value of ¹⁸F-FDG PET/CT at initial diagnosis and 1-year follow-up |
journalArticle |
2015 |
Lepoutre-Lussey, C.; Caramella, C.; Bidault, F.; Déandreis, D.; Berdelou, A.; Al Ghuzlan, A.; Hartl, D.; Borget, I.; Gimenez-Roqueplo, A. P.; Dumont, F.; Deschamps, F.; Nascimento, C.; Lumbroso, J.; Guillaud Bataille, M.; Schlumberger, M.; Baudin, E.; Leboulleux, S. |
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Low response rate after cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: long-term results of the UNICANCER ACCORD 16 phase II trial |
journalArticle |
2015 |
Levy, A.; Azria, D.; Pignon, J. P.; Delarochefordiere, A.; Martel-Lafay, I.; Rio, E.; Malka, D.; Conroy, T.; Miglianico, L.; Becouarn, Y.; Malekzadeh, K.; Leclercq, J.; Juzyna, B.; Ezra, P.; Lemanski, C.; Deutsch, E. |
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Late toxicity of brachytherapy after female genital tract tumors treated during childhood: Prospective evaluation with a long-term follow-up |
journalArticle |
2015 |
Levy, A.; Martelli, H.; Fayech, C.; Minard-Colin, V.; Dumas, I.; Gensse, M. C.; Le Deley, M. C.; Oberlin, O.; Haie-Meder, C. |
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REBECA: a phase I study of bevacizumab and whole-brain radiation therapy for the treatment of brain metastasis from solid tumours |
journalArticle |
2015 |
Levy, C.; Allouache, D.; Lacroix, J.; Dugue, A. E.; Supiot, S.; Campone, M.; Mahe, M.; Kichou, S.; Leheurteur, M.; Hanzen, C.; Dieras, V.; Kirova, Y.; Campana, F.; Le Rhun, E.; Gras, L.; Bachelot, T.; Sunyach, M. P.; Hrab, I.; Geffrelot, J.; Gunzer, K.; Constans, J. M.; Grellard, J. M.; Clarisse, B.; Paoletti, X. |
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Mining the coding and non-coding genome for cancer drivers |
journalArticle |
2015 |
Li, J.; Drubay, D.; Michiels, S.; Gautheret, D. |
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Prognostic factors in stage III-IV adrenocortical carcinomas (ACC): an European Network for the Study of Adrenal Tumor (ENSAT) study |
journalArticle |
2015 |
Libé, R.; Borget, I.; Ronchi, C. L.; Zaggia, B.; Kroiss, M.; Kerkhofs, T.; Bertherat, J.; Volante, M.; Quinkler, M.; Chabre, O.; Bala, M.; Tabarin, A.; Beuschlein, F.; Vezzosi, D.; Deutschbein, T.; Borson-Chazot, F.; Hermsen, I.; Stell, A.; Fottner, C.; Leboulleux, S.; Hahner, S.; Mannelli, M.; Berruti, A.; Haak, H.; Terzolo, M.; Fassnacht, M.; Baudin, E. |
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[uPA/PAI-1, Oncotype DX™, MammaPrint(®). Prognosis and predictive values for clinical utility in breast cancer management] |
journalArticle |
2015 |
Luporsi, E.; Bellocq, J. P.; Barrière, J.; Bonastre, J.; Chetritt, J.; Le Corroller, A. G.; de Cremoux, P.; Fina, F.; Gauchez, A. S.; Lamy, P. J.; Martin, P. M.; Mazouni, C.; Peyrat, J. P.; Romieu, G.; Verdoni, L.; Mazeau-Woynar, V.; Kassab-Chahmi, D. |
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Impact of prophylactic central neck dissection on oncologic outcomes of papillary thyroid carcinoma: a review |
journalArticle |
2015 |
Mamelle, E.; Borget, I.; Leboulleux, S.; Mirghani, H.; Suárez, C.; Pellitteri, P. K.; Shaha, A. R.; Hamoir, M.; Robbins, K. T.; Khafif, A.; Rodrigo, J. P.; Silver, C. E.; Rinaldo, A.; Ferlito, A.; Hartl, D. M. |
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Designs of preoperative biomarkers trials in oncology: a systematic review of the literature |
journalArticle |
2015 |
Marous, M.; Bieche, I.; Paoletti, X.; Alt, M.; Razak, A. R.; Stathis, A.; Kamal, M.; Le Tourneau, C. |
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INTRODUCTION OF INNOVATIVE MEDICAL DEVICES AT FRENCH UNIVERSITY HOSPITALS: AN OVERVIEW OF HOSPITAL-BASED HEALTH TECHNOLOGY ASSESSMENT INITIATIVES |
journalArticle |
2015 |
Martelli, N.; Billaux, M.; Borget, I.; Pineau, J.; Prognon, P.; van den Brink, H. |
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Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status |
journalArticle |
2015 |
Messai, Y.; Gad, S.; Noman, M. Z.; Le Teuff, G.; Couve, S.; Janji, B.; Kammerer, S. F.; Rioux-Leclerc, N.; Hasmim, M.; Ferlicot, S.; Baud, V.; Mejean, A.; Mole, D. R.; Richard, S.; Eggermont, A. M.; Albiges, L.; Mami-Chouaib, F.; Escudier, B.; Chouaib, S. |
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How to Model Survival In Cost-Effectiveness Analysis? Differences Between Markov and Partitioned Survival Analysis Models |
journalArticle |
2015 |
Minacori, R.; Bonastre, J.; Lueza, B.; Marguet, S.; Levy, P. |
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Non-Hodgkin Lymphoma in Children and Adolescents: Progress Through Effective Collaboration, Current Knowledge, and Challenges Ahead |
journalArticle |
2015 |
Minard-Colin, V.; Brugières, L.; Reiter, A.; Cairo, M. S.; Gross, T. G.; Woessmann, W.; Burkhardt, B.; Sandlund, J. T.; Williams, D.; Pillon, M.; Horibe, K.; Auperin, A.; Le Deley, M. C.; Zimmerman, M.; Perkins, S. L.; Raphael, M.; Lamant, L.; Klapper, W.; Mussolin, L.; Poirel, H. A.; Macintyre, E.; Damm-Welk, C.; Rosolen, A.; Patte, C. |
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Treatment de-escalation in HPV-positive oropharyngeal carcinoma: ongoing trials, critical issues and perspectives |
journalArticle |
2015 |
Mirghani, H.; Amen, F.; Blanchard, P.; Moreau, F.; Guigay, J.; Hartl, D. M.; Lacau St Guily, J. |
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Telomere shortening: a new prognostic factor for cardiovascular disease post-radiation exposure |
journalArticle |
2015 |
M'Kacher, R.; Girinsky, T.; Colicchio, B.; Ricoul, M.; Dieterlen, A.; Jeandidier, E.; Heidingsfelder, L.; Cuceu, C.; Shim, G.; Frenzel, M.; Lenain, A.; Morat, L.; Bourhis, J.; Hempel, W. M.; Koscielny, S.; Paul, J. F.; Carde, P.; Sabatier, L. |
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Postoperative fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography: an important imaging modality in patients with aggressive histology of differentiated thyroid cancer |
journalArticle |
2015 |
Nascimento, C.; Borget, I.; Al Ghuzlan, A.; Deandreis, D.; Hartl, D.; Lumbroso, J.; Berdelou, A.; Lepoutre-Lussey, C.; Mirghani, H.; Baudin, E.; Schlumberger, M.; Leboulleux, S. |
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Long-term follow-up of TaG1 non-muscle-invasive bladder cancer |
journalArticle |
2015 |
Olivier Bosset, P.; Neuzillet, Y.; Paoletti, X.; Molinie, V.; Botto, H.; Lebret, T. |
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High level of chromosomal instability in circulating tumor cells of ROS1-rearranged non-small-cell lung cancer |
journalArticle |
2015 |
Pailler, E.; Auger, N.; Lindsay, C. R.; Vielh, P.; Islas-Morris-Hernandez, A.; Borget, I.; Ngo-Camus, M.; Planchard, D.; Soria, J. C.; Besse, B.; Farace, F. |
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Percutaneous lung thermal ablation of non-surgical clinical N0 non-small cell lung cancer: results of eight years' experience in 87 patients from two centers |
journalArticle |
2015 |
Palussiere, J.; Lagarde, P.; Auperin, A.; Deschamps, F.; Chomy, F.; de Baere, T. |
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Design and statistical principles of the SHIVA trial |
journalArticle |
2015 |
Paoletti, X.; Asselain, B.; Kamal, M.; Servant, N.; Huppe, P.; Bieche, I.; Le Tourneau, C. |
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Dose finding with longitudinal data: simpler models, richer outcomes |
journalArticle |
2015 |
Paoletti, X.; Doussau, A.; Ezzalfani, M.; Rizzo, E.; Thiebaut, R. |
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Statistical controversies in clinical research: requiem for the 3 + 3 design for phase I trials |
journalArticle |
2015 |
Paoletti, X.; Ezzalfani, M.; Le Tourneau, C. |
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Locoregional symptoms in patients with de novo metastatic prostate cancer: Morbidity, management, and disease outcome |
journalArticle |
2015 |
Patrikidou, A.; Brureau, L.; Casenave, J.; Albiges, L.; Di Palma, M.; Patard, J. J.; Baumert, H.; Blanchard, P.; Bossi, A.; Kitikidou, K.; Massard, C.; Fizazi, K.; Blanchet, P.; Loriot, Y. |
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Cost Of Genome Analysis: The Sanger Sequencing Method |
journalArticle |
2015 |
Perrier, L.; Heinz, D.; Baffert, S.; Zou, Z.; Durand Zaleski, I.; Rouleau, E.; Wang, Q.; Haddad, V.; Bringuier, P.; Merlio, J.; Caumont, C.; Lacroix, L.; Marino, P.; Borget, I. |
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Mortality analyses in the updated French cohort of uranium miners (1946-2007) |
journalArticle |
2015 |
Rage, E.; Caer-Lorho, S.; Drubay, D.; Ancelet, S.; Laroche, P.; Laurier, D. |
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Management of malignant pleural mesothelioma: a French multicenter retrospective study (GFPC 0802 study) |
journalArticle |
2015 |
Raynaud, C.; Greillier, L.; Mazieres, J.; Monnet, I.; Mastroianni, B.; Robinet, G.; Fraboulet, G.; Dixmier, A.; Berard, H.; Lamy, R.; Letreut, J.; Lena, H.; Oliviero, G.; Botta, S.; Vergnenegre, A.; Borget, I.; Chouaid, C. |
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Trends in tobacco-attributable mortality in France |
journalArticle |
2015 |
Ribassin-Majed, L.; Hill, C. |
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Efficacy of vaccination against HPV infection to prevent cervical cancer in France |
journalArticle |
2015 |
Ribassin-Majed, L.; Hill, C.; Lounes, R. |
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Designs of drug-combination phase I trials in oncology: a systematic review of the literature |
journalArticle |
2015 |
Riviere, M. K.; Le Tourneau, C.; Paoletti, X.; Dubois, F.; Zohar, S. |
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[Radiotherapy for nasopharyngeal carcinoma] |
journalArticle |
2016 |
Maingon, P.; Blanchard, P.; Bidault, F.; Calmels, L. |
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MRI-guided brachytherapy in locally advanced cervical cancer: Small bowel [Formula: see text] and [Formula: see text] are not predictive of late morbidity |
journalArticle |
2016 |
Petit, C.; Dumas, I.; Chargari, C.; Martinetti, F.; Maroun, P.; Doyeux, K.; Tailleur, A.; Haie-Meder, C.; Mazeron, R. |
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Quelles exigences pour qu'un biomarqueur puisse être un critère de substitution acceptable ? |
journalArticle |
2016 |
Paoletti, X.; Rotolo, F.; Michiels, S. |
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Dead space closure with quilting suture versus conventional closure with drainage for the prevention of seroma after mastectomy for breast cancer (QUISERMAS): protocol for a multicentre randomised controlled trial |
journalArticle |
2016 |
Ouldamer, L.; Bonastre, J.; Brunet-Houdard, S.; Body, G.; Giraudeau, B.; Caille, A. |
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Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells |
journalArticle |
2016 |
Mittal, D.; Caramia, F.; Michiels, S.; Joensuu, H.; Kellokumpu-Lehtinen, P. L.; Sotiriou, C.; Loi, S.; Smyth, M. J. |
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Diagnosis of HPV driven oropharyngeal cancers: Comparing p16 based algorithms with the RNAscope HPV-test |
journalArticle |
2016 |
Mirghani, H.; Casiraghi, O.; Guerlain, J.; Amen, F.; He, M. X.; Ma, X. J.; Luo, Y.; Mourareau, C.; Drusch, F.; Lakdhar, A. B.; Melkane, A.; St Guily, L.; Badoual, C.; Scoazec, J. Y.; Borget, I.; Auperin, A.; Dalstein, V.; Vielh, P. |
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Statistical controversies in clinical research: prognostic gene signatures are not (yet) useful in clinical practice |
journalArticle |
2016 |
Michiels, S.; Ternes, N.; Rotolo, F. |
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Progression-free survival as surrogate end point for overall survival in clinical trials of HER2-targeted agents in HER2-positive metastatic breast cancer |
journalArticle |
2016 |
Michiels, S.; Pugliano, L.; Marguet, S.; Grun, D.; Barinoff, J.; Cameron, D.; Cobleigh, M.; Di Leo, A.; Johnston, S.; Gasparini, G.; Kaufman, B.; Marty, M.; Nekljudova, V.; Paluch-Shimon, S.; Penault-Llorca, F.; Slamon, D.; Vogel, C.; von Minckwitz, G.; Buyse, M.; Piccart, M. |
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Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents |
journalArticle |
2016 |
Merlevede, J.; Droin, N.; Qin, T.; Meldi, K.; Yoshida, K.; Morabito, M.; Chautard, E.; Auboeuf, D.; Fenaux, P.; Braun, T.; Itzykson, R.; de Botton, S.; Quesnel, B.; Commes, T.; Jourdan, E.; Vainchenker, W.; Bernard, O.; Pata-Merci, N.; Solier, S.; Gayevskiy, V.; Dinger, M. E.; Cowley, M. J.; Selimoglu-Buet, D.; Meyer, V.; Artiguenave, F.; Deleuze, J. F.; Preudhomme, C.; Stratton, M. R.; Alexandrov, L. B.; Padron, E.; Ogawa, S.; Koscielny, S.; Figueroa, M.; Solary, E. |
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Reduced acute toxicity and improved efficacy from intensity-modulated proton therapy (IMPT) for the management of head and neck cancer |
journalArticle |
2016 |
McKeever, M. R.; Sio, T. T.; Gunn, G. B.; Holliday, E. B.; Blanchard, P.; Kies, M. S.; Weber, R. S.; Frank, S. J. |